Evidence brief · Supplement
DHEA for Deficiency (adrenal insufficiency)
Evidence grade B — Under care
- Overall grade
- Grade B
- Last revised
- 1
- graded outcome
- 0
- references listed
Assembled by the app from other entries in this library. It adds no evidence of its own — follow the links to the entries it draws on.
1 at grade B — 1 graded row
What is known
Each outcome with its grade (how strong the evidence is, A to D), the size of the effect where the entry records one, and how often studies agree.
- Deficiency (adrenal insufficiency)Evidence grade B
Under care
Moderatemixed
What is uncertain
Read off the same rows as above. Nothing here is added that the entry does not itself record.
- Studies disagree: Deficiency (adrenal insufficiency) (mixed agreement).
The evidence in words
The verdict
For deficiency (adrenal insufficiency), DHEA earns evidence grade B (moderate effect, mixed consistency) — there is real evidence here. Under care
How it might work
Supplementation raises DHEA and downstream sex-hormone levels, with effects that depend heavily on age, sex, and baseline status.
How to use it
Only under medical supervision against measured low levels; self-dosing a hormone is ill-advised.
Safety & cautions
Hormonal side effects (acne, hair changes, and hormone-sensitive-cancer concerns); it is not a benign supplement. Banned by anti-doping agencies.
Bottom line
This is a hormone, not a vitamin. Useful in true deficiency under a clinician; not for healthy people, and off-limits for tested athletes.
How it is used
As the entry records it, from the studies it summarises. Not a recommendation for you — doses that suit a trial population may not suit you.
- Medical only
- Under supervision against low measured levels.
Goes with
- DHEARead the full DHEA monographEvidence grade C
Related reading
Entries that share this one's tags or conditions.
- DHEA for Wellbeing (healthy young)Evidence grade D — Little benefit, real riskEvidence grade D
- DHEA: dosage and how to take itUnder supervision against low measured levels.Evidence grade C
- DHEA: side effects, safety & interactionsHormonal side effects (acne, hair changes, and hormone-sensitive-cancer concerns); it is not a benign supplement. BannedEvidence grade C
- Pregnenolone for Memory / moodEvidence grade D — Weak, oldEvidence grade D
Sources
This entry lists no references of its own — it is assembled from the entries it links to, whose sources are on their pages.
Last revised . A grade is this entry's reading of the evidence, not medical advice.