Evidence brief · Supplement
D-Mannose for Recurrent UTI prevention
Evidence grade C — Small trials
- Overall grade
- Grade C
- Last revised
- 1
- graded outcome
- 0
- references listed
Assembled by the app from other entries in this library. It adds no evidence of its own — follow the links to the entries it draws on.
1 at grade C — 1 graded row
What is known
Each outcome with its grade (how strong the evidence is, A to D), the size of the effect where the entry records one, and how often studies agree.
- Recurrent UTI preventionEvidence grade C
Small trials
Moderatemixed
What is uncertain
Read off the same rows as above. Nothing here is added that the entry does not itself record.
- Thin evidence: Recurrent UTI prevention (grade C).
The evidence in words
The verdict
For recurrent uti prevention, D-Mannose earns evidence grade C (moderate effect, mixed consistency) — the evidence is limited or mixed. Small trials
How it might work
It binds the adhesion molecules E. coli use to grip the bladder wall, letting them flush out in urine.
How to use it
2 g/day for prevention; higher split doses in some protocols.
Safety & cautions
Well tolerated; caution in diabetes (it is a sugar, though minimally metabolized).
Bottom line
A promising, low-side-effect UTI-prevention option, often with cranberry. Early but encouraging.
How it is used
As the entry records it, from the studies it summarises. Not a recommendation for you — doses that suit a trial population may not suit you.
- Standard
- 2 g/day for prevention.
Goes with
- D-MannoseRead the full D-Mannose monographEvidence grade C
Related reading
Entries that share this one's tags or conditions.
- Cranberry for Recurrent UTI preventionEvidence grade B — In susceptible groupsEvidence grade B
- Cranberry for Active UTI treatmentEvidence grade D — Not a treatmentEvidence grade D
- Cranberry for Recurrent urinary-tract infectionEvidence grade B — PreventionEvidence grade B
- D-Mannose for Recurrent urinary-tract infectionEvidence grade C — PreventionEvidence grade C
Sources
This entry lists no references of its own — it is assembled from the entries it links to, whose sources are on their pages.
Last revised . A grade is this entry's reading of the evidence, not medical advice.