Vitamin E and Vitamin E for All-cause mortality (high dose)
Each entry’s own grades, side by side. A grade says how strong the evidence is for one outcome — it does not rank one entry over the other.
Compound or practice
Vitamin E
A fat-soluble antioxidant that fixes a rare deficiency and, at high doses, disappointed almost every disease-prevention trial it entered.
Grade C3 graded outcomesrevised Jul 10, 2026
A structured monograph in Prometheus's bundled library. Its grades are the monograph's own reading of the evidence, not a peer-reviewed review.
Evidence brief
Vitamin E for All-cause mortality (high dose)
Evidence grade C — Meta-analysis suggests slight increase ≥400 IU
Grade C1 graded outcomerevised Jul 10, 2026
Assembled by the app from other entries in this library. It adds no evidence of its own — follow the links to the entries it draws on.
Graded in both
Outcomes are matched by name. Two entries can describe the same outcome in different words, so one listed further down may still be graded in the other.
| Outcome | Vitamin E | Vitamin E for All-cause mortality (high dose) |
|---|---|---|
| All-cause mortality (high dose) | Evidence grade CSmall effectmixedMeta-analysis suggests slight increase ≥400 IU | Evidence grade CSmall effectmixedMeta-analysis suggests slight increase ≥400 IU |
Graded only in Vitamin E
- CVD / cancer prevention Trivial effectEvidence grade D
- NAFLD/NASH histology Moderate effectEvidence grade B
Graded only in Vitamin E for All-cause mortality (high dose)
None — every outcome it grades is graded in both.
What each entry says about the other
- Vitamin E for All-cause mortality (high dose)’s entry · Goes with: Read the full Vitamin E monograph
Both columns are read from the entries as they stand in this library. A comparison is not advice to take either one, and it is no substitute for a clinician who knows the person.