Vitamin D and Supplements for bone health
Each entry’s own grades, side by side. A grade says how strong the evidence is for one outcome — it does not rank one entry over the other.
Compound or practice
Vitamin D
A steroid hormone precursor that most temperate-latitude adults run low on — worth correcting, oversold as a cure-all.
Grade A5 graded outcomesrevised Jul 10, 2026
A structured monograph in Prometheus's bundled library. Its grades are the monograph's own reading of the evidence, not a peer-reviewed review.
Goal guide
Supplements for bone health
7 compounds relevant to bone health, ranked by overall evidence grade.
Grade A7 graded outcomesrevised Jul 10, 2026
Assembled by the app from other entries in this library. It adds no evidence of its own — follow the links to the entries it draws on.
Graded in both
Outcomes are matched by name. Two entries can describe the same outcome in different words, so one listed further down may still be graded in the other.
No outcome has the same name in both entries. They may still overlap under different wording — read the two lists below.
Graded only in Vitamin D
- Correcting deficiency (25(OH)D) Large effectEvidence grade A
- Fracture / fall risk (deficient elderly + calcium) Moderate effectEvidence grade B
- Respiratory infection risk Small effectEvidence grade C
- Cancer / CVD prevention (replete adults) Trivial effectEvidence grade D
- Type 2 diabetes prevention Trivial effectEvidence grade D
Graded only in Supplements for bone health
- Vitamin D Unclear effectEvidence grade A
- Vitamin K2 Unclear effectEvidence grade B
- Calcium Unclear effectEvidence grade B
- Phosphorus Unclear effectEvidence grade B
- Silicon Unclear effectEvidence grade C
- Cissus Quadrangularis Unclear effectEvidence grade C
- Strontium Unclear effectEvidence grade C
Conditions
Only in Vitamin D
- Osteoporosis / bone loss May improveEvidence grade B
- Seasonal low mood May improveEvidence grade C
- Autoimmune disease No clear effectEvidence grade C
Only in Supplements for bone health
None.
What each entry says about the other
- Supplements for bone health’s entry · Goes with: Grade A
Both columns are read from the entries as they stand in this library. A comparison is not advice to take either one, and it is no substitute for a clinician who knows the person.