PrometheusGeneral

LDL cholesterol: what the evidence supports and Plant Sterols / Stanols

Each entry’s own grades, side by side. A grade says how strong the evidence is for one outcome — it does not rank one entry over the other.

Outcome map

LDL cholesterol: what the evidence supports

11 graded interventions for ldl cholesterol, ranked by strength of evidence.

Grade A11 graded outcomesrevised Jul 10, 2026

Assembled by the app from other entries in this library. It adds no evidence of its own — follow the links to the entries it draws on.

Compound or practice

Plant Sterols / Stanols

Fortified-food compounds that reliably shave LDL by blocking cholesterol absorption — proven biomarker, uncertain hard outcomes.

Grade A2 graded outcomesrevised Jul 10, 2026

A structured monograph in Prometheus's bundled library. Its grades are the monograph's own reading of the evidence, not a peer-reviewed review.

Swap the two

Graded in both

Outcomes are matched by name. Two entries can describe the same outcome in different words, so one listed further down may still be graded in the other.

No outcome has the same name in both entries. They may still overlap under different wording — read the two lists below.

Graded only in LDL cholesterol: what the evidence supports

  • Psyllium Husk Small effectEvidence grade A
  • Red Yeast Rice Moderate effectEvidence grade A
  • Plant Sterols / Stanols Moderate effectEvidence grade A
  • Glucomannan Small effectEvidence grade B
  • Beta-Sitosterol Small effectEvidence grade B
  • Garlic Small effectEvidence grade C
  • Artichoke Leaf Extract Small effectEvidence grade C
  • Tocotrienols Small effectEvidence grade C
  • Black Seed Oil (Nigella sativa) Small effectEvidence grade C
  • Guggul Trivial effectEvidence grade D
  • Policosanol Trivial effectEvidence grade D

Graded only in Plant Sterols / Stanols

  • LDL cholesterol Moderate effectEvidence grade A
  • Cardiovascular events Unclear effectEvidence grade C

What each entry says about the other

  • LDL cholesterol: what the evidence supports’s entry · Goes with: Grade A

Both columns are read from the entries as they stand in this library. A comparison is not advice to take either one, and it is no substitute for a clinician who knows the person.