Niacin (B3) and Cardiovascular events: what the evidence supports
Each entry’s own grades, side by side. A grade says how strong the evidence is for one outcome — it does not rank one entry over the other.
Compound or practice
Niacin (B3)
Corrects pellagra, powerfully shifts blood lipids — but as a heart drug it failed to cut events and added harm.
Grade B4 graded outcomesrevised Jul 10, 2026
A structured monograph in Prometheus's bundled library. Its grades are the monograph's own reading of the evidence, not a peer-reviewed review.
Outcome map
Cardiovascular events: what the evidence supports
4 graded interventions for cardiovascular events, ranked by strength of evidence.
Grade B4 graded outcomesrevised Jul 10, 2026
Assembled by the app from other entries in this library. It adds no evidence of its own — follow the links to the entries it draws on.
Graded in both
Outcomes are matched by name. Two entries can describe the same outcome in different words, so one listed further down may still be graded in the other.
No outcome has the same name in both entries. They may still overlap under different wording — read the two lists below.
Graded only in Niacin (B3)
- Pellagra Large effectEvidence grade A
- HDL / triglycerides Large effectEvidence grade A
- Cardiovascular events Trivial effectEvidence grade D
- Non-melanoma skin cancer (nicotinamide) Small effectEvidence grade B
Graded only in Cardiovascular events: what the evidence supports
- Red Yeast Rice Moderate effectEvidence grade B
- Plant Sterols / Stanols Unclear effectEvidence grade C
- Folate (B9) Trivial effectEvidence grade D
- Niacin (B3) Trivial effectEvidence grade D
What each entry says about the other
- Cardiovascular events: what the evidence supports’s entry · Goes with: Grade D
Both columns are read from the entries as they stand in this library. A comparison is not advice to take either one, and it is no substitute for a clinician who knows the person.