PrometheusGeneral

Berberine + Immunosuppressants: use with caution and Berberine

Each entry’s own grades, side by side. A grade says how strong the evidence is for one outcome — it does not rank one entry over the other.

Interaction

Berberine + Immunosuppressants: use with caution

Berberine inhibits CYP3A4/P-gp, raising cyclosporine/tacrolimus levels.

Grade B0 graded outcomesrevised Jul 10, 2026

Assembled by the app from other entries in this library. It adds no evidence of its own — follow the links to the entries it draws on.

Compound or practice

Berberine

A plant alkaloid that behaves like a metabolic drug — real glucose and lipid effects, and it deserves drug-level caution.

Grade B2 graded outcomesrevised Jul 10, 2026

A structured monograph in Prometheus's bundled library. Its grades are the monograph's own reading of the evidence, not a peer-reviewed review.

Swap the two

Graded in both

Outcomes are matched by name. Two entries can describe the same outcome in different words, so one listed further down may still be graded in the other.

No outcome has the same name in both entries. They may still overlap under different wording — read the two lists below.

Graded only in Berberine + Immunosuppressants: use with caution

None — every outcome it grades is graded in both.

Graded only in Berberine

  • Fasting glucose / HbA1c Moderate effectEvidence grade B
  • LDL / triglycerides Small effectEvidence grade B

Conditions

Only in Berberine + Immunosuppressants: use with caution

None.

Only in Berberine

What each entry says about the other

  • Berberine + Immunosuppressants: use with caution’s entry · Watch with: About Berberine

Both columns are read from the entries as they stand in this library. A comparison is not advice to take either one, and it is no substitute for a clinician who knows the person.