HMB and HMB for Muscle (trained, adequate protein)
Each entry’s own grades, side by side. A grade says how strong the evidence is for one outcome — it does not rank one entry over the other.
Compound or practice
HMB
A leucine metabolite that mainly helps the untrained and the catabolic — largely redundant for seasoned lifters eating enough protein.
Grade C2 graded outcomesrevised Jul 10, 2026
A structured monograph in Prometheus's bundled library. Its grades are the monograph's own reading of the evidence, not a peer-reviewed review.
Evidence brief
HMB for Muscle (trained, adequate protein)
Evidence grade D — Little added benefit
Grade D1 graded outcomerevised Jul 10, 2026
Assembled by the app from other entries in this library. It adds no evidence of its own — follow the links to the entries it draws on.
Graded in both
Outcomes are matched by name. Two entries can describe the same outcome in different words, so one listed further down may still be graded in the other.
| Outcome | HMB | HMB for Muscle (trained, adequate protein) |
|---|---|---|
| Muscle (trained, adequate protein) | Evidence grade DTrivial effectmixedLittle added benefit | Evidence grade DTrivial effectmixedLittle added benefit |
Graded only in HMB
- Muscle (untrained / catabolic) Small effectEvidence grade C
Graded only in HMB for Muscle (trained, adequate protein)
None — every outcome it grades is graded in both.
What each entry says about the other
- HMB for Muscle (trained, adequate protein)’s entry · Goes with: Read the full HMB monograph
Both columns are read from the entries as they stand in this library. A comparison is not advice to take either one, and it is no substitute for a clinician who knows the person.