Cranberry and D-Mannose

Each entry’s own grades, side by side. A grade says how strong the evidence is for one outcome — it does not rank one entry over the other.

Compound or practice

Cranberry

Genuinely reduces recurrent UTIs via proanthocyanidins — prevention, not treatment.

Grade B2 graded outcomesrevised Jul 10, 2026

A structured monograph in Prometheus's bundled library. Its grades are the monograph's own reading of the evidence, not a peer-reviewed review.

Compound or practice

D-Mannose

A simple sugar that helps flush UTI-causing E. coli — promising early data for prevention.

Grade C1 graded outcomerevised Jul 10, 2026

A structured monograph in Prometheus's bundled library. Its grades are the monograph's own reading of the evidence, not a peer-reviewed review.

Swap the two

Graded in both

Outcomes are matched by name. Two entries can describe the same outcome in different words, so one listed further down may still be graded in the other.

OutcomeCranberryD-Mannose
Recurrent UTI prevention
Evidence grade BModerate effectmixedIn susceptible groups
Evidence grade CModerate effectmixedSmall trials

Graded only in Cranberry

  • Active UTI treatment Trivial effectEvidence grade D

Graded only in D-Mannose

None — every outcome it grades is graded in both.

Conditions

Only in Cranberry

None.

Only in D-Mannose

None.

What each entry says about the other

  • Cranberry’s entry · Works together: Both target E. coli adhesion — common UTI-prevention pairing.
  • Cranberry’s entry · Goes with: Both target E. coli adhesion — common UTI-prevention pairing.
  • D-Mannose’s entry · Works together: Complementary anti-adhesion — common pairing.
  • D-Mannose’s entry · Goes with: Complementary anti-adhesion — common pairing.

Both columns are read from the entries as they stand in this library. A comparison is not advice to take either one, and it is no substitute for a clinician who knows the person.