Coenzyme Q10 and Coenzyme Q10 + Statins: one depletes the other
Each entry’s own grades, side by side. A grade says how strong the evidence is for one outcome — it does not rank one entry over the other.
Compound or practice
Coenzyme Q10
A mitochondrial cofactor with its best evidence in heart failure and statin-associated muscle symptoms.
Grade B3 graded outcomesrevised Jul 10, 2026
A structured monograph in Prometheus's bundled library. Its grades are the monograph's own reading of the evidence, not a peer-reviewed review.
Interaction
Coenzyme Q10 + Statins: one depletes the other
Statins lower CoQ10 ~30–50%; repletion may ease muscle symptoms.
Grade B0 graded outcomesrevised Jul 10, 2026
Assembled by the app from other entries in this library. It adds no evidence of its own — follow the links to the entries it draws on.
Graded in both
Outcomes are matched by name. Two entries can describe the same outcome in different words, so one listed further down may still be graded in the other.
No outcome has the same name in both entries. They may still overlap under different wording — read the two lists below.
Graded only in Coenzyme Q10
- Heart failure events Moderate effectEvidence grade B
- Statin muscle symptoms Small effectEvidence grade C
- Migraine prophylaxis Small effectEvidence grade C
Graded only in Coenzyme Q10 + Statins: one depletes the other
None — every outcome it grades is graded in both.
Conditions
Only in Coenzyme Q10
- Chronic heart failure May improveEvidence grade B
Only in Coenzyme Q10 + Statins: one depletes the other
None.
What each entry says about the other
- Coenzyme Q10 + Statins: one depletes the other’s entry · Watch with: About Coenzyme Q10
Both columns are read from the entries as they stand in this library. A comparison is not advice to take either one, and it is no substitute for a clinician who knows the person.