Compound or practice · Supplement
Turkesterone
A viral 'natural anabolic' ecdysteroid with essentially no human trials behind the hype.
- Overall grade
- Grade D
- Last revised
- 1
- graded outcome
- 0
- references listed
A structured monograph in Prometheus's bundled library. Its grades are the monograph's own reading of the evidence, not a peer-reviewed review.
1 at grade D — 1 graded row
What is known
Each outcome with its grade (how strong the evidence is, A to D), the size of the effect where the entry records one, and how often studies agree.
- Muscle / performanceEvidence grade D
No human RCTs
Unclearlow
What is uncertain
Read off the same rows as above. Nothing here is added that the entry does not itself record.
- Thin evidence: Muscle / performance (grade D).
The evidence in words
What it is
Turkesterone is an ecdysteroid from Ajuga turkestanica that went viral on social media as a muscle-builder.
How it works
Proposed, like ecdysterone, to raise protein synthesis via estrogen-receptor-beta — but this is extrapolated from animal and cell data, not shown in humans.
What the evidence shows
There are no published human RCTs on turkesterone for muscle or performance; the claims ride on rodent studies and marketing. Third-party testing has also found many products under-dosed or adulterated.
Safety & interactions
Human safety data are essentially absent; some users report GI upset and nausea. Quality/adulteration is a real concern.
Bottom line
Hype far outrunning evidence — no human trials, dubious products. Save your money until real data exist.
Related reading
Entries that share this one's tags or conditions.
- EcdysteroneAn insect/plant steroid with one surprisingly positive muscle trial — interesting, under-replicated, and dose-uncertain.Evidence grade C
- Ecdysterone for Strength / lean massEvidence grade C — One trial, unreplicatedEvidence grade C
- Ecdysterone: side effects, safety & interactionsAppears well tolerated short-term; long-term and dosing data are thin. It's on WADA's monitoring list for athletes.Evidence grade C
- Turkesterone for Muscle / performanceEvidence grade D — No human RCTsEvidence grade D
Sources
This entry lists no references of its own.
Last revised . A grade is this entry's reading of the evidence, not medical advice.