Migraine prophylaxis: what the evidence supports

2 graded interventions for migraine prophylaxis, ranked by strength of evidence.

Overall grade: Grade B
Last revised: Jul 10, 2026; 2
graded outcomes: 0
references listed

Assembled by the app from other entries in this library. It adds no evidence of its own — follow the links to the entries it draws on.

1 at grade B · 1 at grade C — 2 graded rows

What is known

Each outcome with its grade (how strong the evidence is, A to D), the size of the effect where the entry records one, and how often studies agree.

Outcome	Grade	Effect size	Agreement
MagnesiumRecommended by some guidelines	Evidence grade B	Moderate	mixed
Coenzyme Q10Modest	Evidence grade C	Small	mixed

MagnesiumEvidence grade B
Recommended by some guidelines
Moderatemixed
Coenzyme Q10Evidence grade C
Modest
Smallmixed

What is uncertain

Read off the same rows as above. Nothing here is added that the entry does not itself record.

Thin evidence: Coenzyme Q10 (grade C).
Studies disagree: Magnesium (mixed agreement).

The evidence in words

The evidence map

This is the ranked evidence for migraine prophylaxis: every compound in the knowledge base with a graded effect, best-supported first. Grades reflect replication and effect size, not popularity or marketing.

Best-supported

Magnesium (grade B) — Recommended by some guidelines

Weaker or unproven

Coenzyme Q10 (grade C) — Modest

Goes with

MagnesiumGrade BEvidence grade B
Coenzyme Q10Grade CEvidence grade B

Entries that share this one's tags or conditions.

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Antibiotic-associated diarrhea: what the evidence supports2 graded interventions for antibiotic-associated diarrhea, ranked by strength of evidence.Evidence grade B
Anxiety: what the evidence supports6 graded interventions for anxiety, ranked by strength of evidence.Evidence grade B
Benign prostatic hyperplasia: what the evidence supports3 graded interventions for benign prostatic hyperplasia, ranked by strength of evidence.Evidence grade C

Sources

This entry lists no references of its own — it is assembled from the entries it links to, whose sources are on their pages.

Last revised Jul 10, 2026. A grade is this entry's reading of the evidence, not medical advice.