Menopause symptoms: what the evidence supports

3 graded interventions for menopause symptoms, ranked by strength of evidence.

Overall grade: Grade B
Last revised: Jul 10, 2026; 3
graded outcomes: 0
references listed

Assembled by the app from other entries in this library. It adds no evidence of its own — follow the links to the entries it draws on.

1 at grade B · 2 at grade C — 3 graded rows

What is known

Each outcome with its grade (how strong the evidence is, A to D), the size of the effect where the entry records one, and how often studies agree.

Outcome	Grade	Effect size	Agreement
Soy IsoflavonesHot flashes	Evidence grade B	Unclear	mixed
Black CohoshInconsistent	Evidence grade C	Unclear	mixed
Red CloverInconsistent	Evidence grade C	Unclear	mixed

Soy IsoflavonesEvidence grade B
Hot flashes
Unclearmixed
Black CohoshEvidence grade C
Inconsistent
Unclearmixed
Red CloverEvidence grade C
Inconsistent
Unclearmixed

What is uncertain

Read off the same rows as above. Nothing here is added that the entry does not itself record.

Thin evidence: Black Cohosh (grade C); Red Clover (grade C).
Studies disagree: Soy Isoflavones (mixed agreement).

The evidence in words

The evidence map

This is the ranked evidence for menopause symptoms: every compound in the knowledge base with a graded effect, best-supported first. Grades reflect replication and effect size, not popularity or marketing.

Best-supported

Soy Isoflavones (grade B) — Hot flashes

Weaker or unproven

Black Cohosh (grade C) — Inconsistent · Red Clover (grade C) — Inconsistent

Goes with

Soy IsoflavonesGrade BEvidence grade B
Black CohoshGrade CEvidence grade C
Red CloverGrade CEvidence grade C

Entries that share this one's tags or conditions.

Allergic rhinitis: what the evidence supports3 graded interventions for allergic rhinitis, ranked by strength of evidence.Evidence grade B
Antibiotic-associated diarrhea: what the evidence supports2 graded interventions for antibiotic-associated diarrhea, ranked by strength of evidence.Evidence grade B
Anxiety: what the evidence supports6 graded interventions for anxiety, ranked by strength of evidence.Evidence grade B
Benign prostatic hyperplasia: what the evidence supports3 graded interventions for benign prostatic hyperplasia, ranked by strength of evidence.Evidence grade C

Sources

This entry lists no references of its own — it is assembled from the entries it links to, whose sources are on their pages.

Last revised Jul 10, 2026. A grade is this entry's reading of the evidence, not medical advice.