Compound or practice · Supplement
Silicon
A trace element with modest bone and hair/skin/nail signals via collagen support.
- Overall grade
- Grade C
- Last revised
- 2
- graded outcomes
- 0
- references listed
A structured monograph in Prometheus's bundled library. Its grades are the monograph's own reading of the evidence, not a peer-reviewed review.
2 at grade C — 2 graded rows
What is known
Each outcome with its grade (how strong the evidence is, A to D), the size of the effect where the entry records one, and how often studies agree.
- Bone-mineral densityEvidence grade C
Observational + small trials
Smallmixed
- Hair/skin/nailsEvidence grade C
Collagen support
Smallmixed
What is uncertain
Read off the same rows as above. Nothing here is added that the entry does not itself record.
- Thin evidence: Bone-mineral density (grade C); Hair/skin/nails (grade C).
Interactions
Documented pairings with supplements and medicines. A medicine on this list is a conversation for whoever prescribes it.
Collagen PeptidesWorks together
Both support connective-tissue synthesis.
The evidence in words
What it is
Bioavailable silicon (orthosilicic acid) is studied for bone density and connective tissue.
How it works
Silicon supports collagen and glycosaminoglycan synthesis, relevant to bone matrix, skin, hair, and nails.
What the evidence shows
Observational and small trial data link silicon intake to better bone-mineral density and some hair/nail/skin measures; evidence is limited but consistent in direction. Low-risk.
How to use it
Bioavailable orthosilicic acid or choline-stabilized forms; modest daily dose.
Safety & interactions
Safe at supplemental doses. Collagen Peptides — Both support connective-tissue synthesis.
Bottom line
A minor connective-tissue and bone support with limited but coherent data. A reasonable low-risk add-on.
How it is used
As the entry records it, from the studies it summarises. Not a recommendation for you — doses that suit a trial population may not suit you.
- Standard
- Bioavailable orthosilicic acid daily.
Goes with
- Collagen PeptidesBoth support connective-tissue synthesis.Evidence grade B
Related reading
Entries that share this one's tags or conditions.
- Silicon for Bone-mineral densityEvidence grade C — Observational + small trialsEvidence grade C
- Silicon for Hair/skin/nailsEvidence grade C — Collagen supportEvidence grade C
- Silicon: dosage and how to take itBioavailable orthosilicic acid daily.Evidence grade C
- Silicon: side effects, safety & interactionsSafe at supplemental doses.Evidence grade C
Sources
This entry lists no references of its own.
Last revised . A grade is this entry's reading of the evidence, not medical advice.