Schisandra

A five-flavor adaptogen berry with liver-support and early stress/endurance signals.

A structured monograph in Prometheus's bundled library. Its grades are the monograph's own reading of the evidence, not a peer-reviewed review.

2 at grade C — 2 graded rows

What is known

Each outcome with its grade (how strong the evidence is, A to D), the size of the effect where the entry records one, and how often studies agree.

Outcome	Grade	Effect size	Agreement
Stress / mental performanceEarly	Evidence grade C	Small	low
Liver enzymesModest	Evidence grade C	Small	mixed

Read off the same rows as above. Nothing here is added that the entry does not itself record.

Schisandra chinensis is an adaptogenic berry (lignans) used for stress resilience, liver health, and endurance.

Its lignans support liver detox enzymes and the stress response, with antioxidant activity.

Mostly traditional and preclinical, with small human signals for stress, mental performance, and liver-enzyme improvement. Promising but thin. Safe.

Standardized lignan extract daily.

Generally safe; may induce liver enzymes affecting some drugs.

A traditional adaptogen with early liver and stress signals. Low-risk; evidence is still building.

As the entry records it, from the studies it summarises. Not a recommendation for you — doses that suit a trial population may not suit you.

Entries that share this one's tags or conditions.

Holy Basil (Tulsi)A gentle adaptogen with early evidence for stress, anxiety, and metabolic markers — promising, thin, low-risk.Evidence grade C
Rhodiola RoseaA stimulating adaptogen with the best fatigue evidence among the herbal 'stress' supplements — daytime energy without ashwagandha's flatness.Evidence grade B
Schisandra for Liver enzymesEvidence grade C — ModestEvidence grade C
Schisandra for Stress / mental performanceEvidence grade C — EarlyEvidence grade C

This entry lists no references of its own.

Last revised Jul 10, 2026. A grade is this entry's reading of the evidence, not medical advice.