Compound or practice · Supplement

Royal Jelly

The queen-bee secretion sold for vitality — modest, real signals for lipids and menopausal symptoms amid a lot of hype.

Overall grade
Grade C
Last revised
2
graded outcomes
0
references listed

A structured monograph in Prometheus's bundled library. Its grades are the monograph's own reading of the evidence, not a peer-reviewed review.

2 at grade C — 2 graded rows

What is known

Each outcome with its grade (how strong the evidence is, A to D), the size of the effect where the entry records one, and how often studies agree.

  • Lipid panel / glucoseEvidence grade C

    Modest

    Smallmixed

  • Menopausal symptomsEvidence grade C

    Small trials

    Smalllow

What is uncertain

Read off the same rows as above. Nothing here is added that the entry does not itself record.

  • Thin evidence: Lipid panel / glucose (grade C); Menopausal symptoms (grade C).

The evidence in words

What it is

Royal jelly is the protein-rich secretion worker bees feed the queen, marketed broadly for energy, hormones and skin.

How it works

It contains unique fatty acids (10-HDA) and proteins with mild estrogenic, antioxidant and lipid-modulating actions.

What the evidence shows

Meta-analyses show royal jelly can modestly improve the lipid panel and glucose, and small trials suggest relief of some menopausal symptoms and better wound healing. The sweeping 'vitality/anti-aging' claims outrun the data.

Safety & interactions

Generally tolerated, but a potent allergen — can cause serious reactions (asthma, anaphylaxis) in sensitive people. Avoid with bee/pollen allergy.

Bottom line

A bee product with modest, real lipid and menopausal signals — but a meaningful allergy risk and a lot of overreach in marketing. Middling.

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Sources

This entry lists no references of its own.

Last revised . A grade is this entry's reading of the evidence, not medical advice.