Compound or practice · Supplement

Lycopene

The tomato carotenoid with modest prostate and cardiovascular signals — better from food than pills.

Overall grade
Grade C
Last revised
2
graded outcomes
0
references listed

A structured monograph in Prometheus's bundled library. Its grades are the monograph's own reading of the evidence, not a peer-reviewed review.

2 at grade C — 2 graded rows

What is known

Each outcome with its grade (how strong the evidence is, A to D), the size of the effect where the entry records one, and how often studies agree.

  • Prostate cancer risk (observational)Evidence grade C

    Food > supplement

    Smallmixed

  • Cardiovascular markersEvidence grade C

    Modest

    Smallmixed

What is uncertain

Read off the same rows as above. Nothing here is added that the entry does not itself record.

  • Thin evidence: Prostate cancer risk (observational) (grade C); Cardiovascular markers (grade C).

The evidence in words

What it is

Lycopene is the red carotenoid in tomatoes, studied for prostate and cardiovascular health.

How it works

A potent antioxidant carotenoid; cooked/processed tomato (with fat) is far more bioavailable than raw.

What the evidence shows

Observational data link tomato/lycopene intake to lower prostate-cancer and cardiovascular risk, but supplement trials are inconsistent. Whole-food tomato products look better than isolated pills.

How to use it

Prefer cooked tomato products with fat; supplements 10–30 mg if used.

Safety & interactions

Safe; harmless skin coloration at very high intake.

Bottom line

Eat cooked tomatoes with olive oil rather than buying pills. Modest, mostly observational benefits.

How it is used

As the entry records it, from the studies it summarises. Not a recommendation for you — doses that suit a trial population may not suit you.

Food-first
Cooked tomato with fat; 10–30 mg if supplementing.

Entries that share this one's tags or conditions.

Sources

This entry lists no references of its own.

Last revised . A grade is this entry's reading of the evidence, not medical advice.