Compound or practice · Supplement
Guarana
A caffeine-rich Amazonian seed — essentially a slow-release caffeine source with the usual stimulant profile.
- Overall grade
- Grade C
- Last revised
- 1
- graded outcome
- 0
- references listed
A structured monograph in Prometheus's bundled library. Its grades are the monograph's own reading of the evidence, not a peer-reviewed review.
1 at grade C — 1 graded row
What is known
Each outcome with its grade (how strong the evidence is, A to D), the size of the effect where the entry records one, and how often studies agree.
- Alertness / metabolic (via caffeine)Evidence grade C
Caffeine-driven
Smallhigh
What is uncertain
Read off the same rows as above. Nothing here is added that the entry does not itself record.
- Thin evidence: Alertness / metabolic (via caffeine) (grade C).
- Caution with Caffeine: It IS caffeine — don't double up.
- Watch with Caffeine: It IS caffeine — don't double up.
Interactions
Documented pairings with supplements and medicines. A medicine on this list is a conversation for whoever prescribes it.
CaffeineCaution
It IS caffeine — don't double up.
The evidence in words
What it is
Guarana is a seed extract very high in caffeine (plus tannins), common in energy drinks and fat-burners.
How it works
Its effects are largely caffeine's, possibly released more slowly due to the tannin matrix.
What the evidence shows
Benefits (alertness, mild metabolic bump) track its caffeine content; independent effects are minor. In fat-burners it's a caffeine source with the associated cardiovascular caveats.
Safety & interactions
Caffeine-driven — jitter, insomnia, cardiovascular load; easy to over-caffeinate in stacks. Caffeine — It IS caffeine — don't double up.
Bottom line
Basically caffeine with extra steps. Fine as a stimulant source; count it toward your caffeine total.
Related reading
Entries that share this one's tags or conditions.
- Guarana for Alertness / metabolic (via caffeine)Evidence grade C — Caffeine-drivenEvidence grade C
- Guarana: side effects, safety & interactionsCaffeine-driven — jitter, insomnia, cardiovascular load; easy to over-caffeinate in stacks.Evidence grade C
- ADHD StimulantsPrescription stimulants for attention-deficit/hyperactivity disorder.Evidence grade A
- Caffeine for Alertness / reaction timeEvidence grade A — Acute, tolerance-limitedEvidence grade A
Sources
This entry lists no references of its own.
Last revised . A grade is this entry's reading of the evidence, not medical advice.