Compound or practice · Supplement

Fo-Ti (He Shou Wu)

A traditional longevity-and-hair tonic with weak evidence and a real liver-toxicity signal.

Overall grade
Grade D
Last revised
1
graded outcome
0
references listed

A structured monograph in Prometheus's bundled library. Its grades are the monograph's own reading of the evidence, not a peer-reviewed review.

1 at grade C — 1 graded row

What is known

Each outcome with its grade (how strong the evidence is, A to D), the size of the effect where the entry records one, and how often studies agree.

  • Liver injuryEvidence grade C

    Documented cases

    Smalllow

What is uncertain

Read off the same rows as above. Nothing here is added that the entry does not itself record.

  • Thin evidence: Liver injury (grade C).

The evidence in words

What it is

Fo-ti (Polygonum multiflorum) is a Chinese tonic used for aging, hair, and vitality.

How it works

Contains stilbenes and anthraquinones with antioxidant and possible hormonal effects.

What the evidence shows

Human evidence is largely traditional; the notable modern finding is documented hepatotoxicity (liver injury) linked to the raw/processed herb. Risk outweighs the thin benefit.

Safety & interactions

Liver-injury reports — a genuine concern; avoid.

Bottom line

Traditional reputation, weak evidence, and a real liver risk. Not recommended.

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Sources

This entry lists no references of its own.

Last revised . A grade is this entry's reading of the evidence, not medical advice.