Evidence brief · Supplement
Soy Isoflavones for Menopausal hot flashes
Evidence grade B — Better in equol producers
- Overall grade
- Grade B
- Last revised
- 1
- graded outcome
- 0
- references listed
Assembled by the app from other entries in this library. It adds no evidence of its own — follow the links to the entries it draws on.
1 at grade B — 1 graded row
What is known
Each outcome with its grade (how strong the evidence is, A to D), the size of the effect where the entry records one, and how often studies agree.
- Menopausal hot flashesEvidence grade B
Better in equol producers
Smallmixed
What is uncertain
Read off the same rows as above. Nothing here is added that the entry does not itself record.
- Studies disagree: Menopausal hot flashes (mixed agreement).
The evidence in words
The verdict
For menopausal hot flashes, Soy Isoflavones earns evidence grade B (small effect, mixed consistency) — there is real evidence here. Better in equol producers
How it might work
They bind estrogen receptors (preferentially ER-beta) with weak estrogen-like activity, modulating menopausal symptoms.
How to use it
40–80 mg isoflavones/day from soy foods or supplements; give it several weeks.
Safety & cautions
Safe at dietary/supplemental doses; discuss with an oncologist if you have hormone-sensitive cancer.
Bottom line
A legitimate, modest option for hot flashes — and the 'soy lowers testosterone' fear is not supported. 40–80 mg/day.
How it is used
As the entry records it, from the studies it summarises. Not a recommendation for you — doses that suit a trial population may not suit you.
- Standard
- 40–80 mg isoflavones/day.
Goes with
- Soy IsoflavonesRead the full Soy Isoflavones monographEvidence grade B
Related reading
Entries that share this one's tags or conditions.
- Red Clover for Menopausal hot flashesEvidence grade C — InconsistentEvidence grade C
- Black Cohosh for Menopausal hot flashesEvidence grade C — Divided trialsEvidence grade C
- Red Clover for Menopause symptomsEvidence grade C — InconsistentEvidence grade C
- Soy Isoflavones for Male testosteroneEvidence grade D — No meaningful effectEvidence grade D
Sources
This entry lists no references of its own — it is assembled from the entries it links to, whose sources are on their pages.
Last revised . A grade is this entry's reading of the evidence, not medical advice.