Evidence brief · Supplement
L-Tyrosine for Cognition when rested
Evidence grade D — No benefit
- Overall grade
- Grade D
- Last revised
- 1
- graded outcome
- 0
- references listed
Assembled by the app from other entries in this library. It adds no evidence of its own — follow the links to the entries it draws on.
1 at grade D — 1 graded row
What is known
Each outcome with its grade (how strong the evidence is, A to D), the size of the effect where the entry records one, and how often studies agree.
- Cognition when restedEvidence grade D
No benefit
Trivialhigh
What is uncertain
Read off the same rows as above. Nothing here is added that the entry does not itself record.
- Thin evidence: Cognition when rested (grade D).
The evidence in words
The verdict
For cognition when rested, L-Tyrosine earns evidence grade D (trivial effect, high consistency) — the evidence does not support the claim. No benefit
How it might work
Under acute stressors — cold, noise, sleep deprivation, cognitive load — catecholamine turnover spikes and tyrosine availability can become limiting. Supplementing may sustain synthesis and protect performance in exactly those conditions.
How to use it
500–2,000 mg taken ~30–60 minutes before an acute stressor or demanding, sleep-deprived session. Not useful as a daily baseline.
Safety & cautions
Well tolerated. Theoretical caution with MAOI antidepressants and thyroid medication; those on such drugs should check first.
Bottom line
Situational, not daily. Take it before a cold, sleepless, or high-pressure cognitive challenge; skip it on ordinary days where it does nothing.
How it is used
As the entry records it, from the studies it summarises. Not a recommendation for you — doses that suit a trial population may not suit you.
- Situational
- 500–2,000 mg, 30–60 min pre-stressor.
Goes with
- L-TyrosineRead the full L-Tyrosine monographEvidence grade C
Related reading
Entries that share this one's tags or conditions.
- L-Tyrosine for Cognition under acute stress / sleep lossEvidence grade C — Condition-specificEvidence grade C
- L-Tyrosine: dosage and how to take it500–2,000 mg, 30–60 min pre-stressor.Evidence grade C
- L-Tyrosine: side effects, safety & interactionsWell tolerated. Theoretical caution with MAOI antidepressants and thyroid medication; those on such drugs should check fEvidence grade C
- Bacopa Monnieri for Acute cognitionEvidence grade D — No same-day effectEvidence grade D
Sources
This entry lists no references of its own — it is assembled from the entries it links to, whose sources are on their pages.
Last revised . A grade is this entry's reading of the evidence, not medical advice.