Evidence brief · Supplement
L-Ornithine for Stress / sleep markers
Evidence grade C — Small studies
- Overall grade
- Grade C
- Last revised
- 1
- graded outcome
- 0
- references listed
Assembled by the app from other entries in this library. It adds no evidence of its own — follow the links to the entries it draws on.
1 at grade C — 1 graded row
What is known
Each outcome with its grade (how strong the evidence is, A to D), the size of the effect where the entry records one, and how often studies agree.
- Stress / sleep markersEvidence grade C
Small studies
Smalllow
What is uncertain
Read off the same rows as above. Nothing here is added that the entry does not itself record.
- Thin evidence: Stress / sleep markers (grade C).
The evidence in words
The verdict
For stress / sleep markers, L-Ornithine earns evidence grade C (small effect, low consistency) — the evidence is limited or mixed. Small studies
How it might work
By supporting ammonia detoxification it may reduce exercise fatigue, and it modestly lowers cortisol/stress markers in small studies.
How to use it
2–6 g/day if trialing, often evening for stress.
Safety & cautions
Well tolerated; GI upset at high doses.
Bottom line
A minor anti-fatigue and stress option with thin evidence. Not essential.
How it is used
As the entry records it, from the studies it summarises. Not a recommendation for you — doses that suit a trial population may not suit you.
- Standard
- 2–6 g/day.
Goes with
- L-OrnithineRead the full L-Ornithine monographEvidence grade C
Related reading
Entries that share this one's tags or conditions.
- L-Ornithine for Exercise fatigueEvidence grade C — Ammonia clearanceEvidence grade C
- L-Ornithine: dosage and how to take it2–6 g/day.Evidence grade C
- L-Ornithine: side effects, safety & interactionsWell tolerated; GI upset at high doses.Evidence grade C
- Panax Ginseng for FatigueEvidence grade C — Small, heterogeneousEvidence grade C
Sources
This entry lists no references of its own — it is assembled from the entries it links to, whose sources are on their pages.
Last revised . A grade is this entry's reading of the evidence, not medical advice.