Evidence brief · Supplement
L-Glutamine for Muscle growth (healthy)
Evidence grade D — No benefit over protein
- Overall grade
- Grade D
- Last revised
- 1
- graded outcome
- 0
- references listed
Assembled by the app from other entries in this library. It adds no evidence of its own — follow the links to the entries it draws on.
1 at grade D — 1 graded row
What is known
Each outcome with its grade (how strong the evidence is, A to D), the size of the effect where the entry records one, and how often studies agree.
- Muscle growth (healthy)Evidence grade D
No benefit over protein
Trivialhigh
What is uncertain
Read off the same rows as above. Nothing here is added that the entry does not itself record.
- Thin evidence: Muscle growth (healthy) (grade D).
The evidence in words
The verdict
For muscle growth (healthy), L-Glutamine earns evidence grade D (trivial effect, high consistency) — the evidence does not support the claim. No benefit over protein
How it might work
It fuels rapidly-dividing gut and immune cells and supports intestinal barrier integrity. In health, the body makes plenty, so extra supplementation has little to act on.
How to use it
Not needed for healthy trainees. Clinical and gut-health uses (5–15 g/day) belong under guidance.
Safety & cautions
Very safe at supplemental doses.
Bottom line
Skip it if you're a healthy lifter — protein intake already covers you. It's a clinical-nutrition tool, not a physique supplement.
How it is used
As the entry records it, from the studies it summarises. Not a recommendation for you — doses that suit a trial population may not suit you.
- Clinical/gut
- 5–15 g/day, under guidance.
Goes with
- L-GlutamineRead the full L-Glutamine monographEvidence grade C
Related reading
Entries that share this one's tags or conditions.
- L-Glutamine for Gut barrier (clinical)Evidence grade C — In catabolic statesEvidence grade C
- L-Glutamine: dosage and how to take it5–15 g/day, under guidance.Evidence grade C
- L-Glutamine: side effects, safety & interactionsVery safe at supplemental doses.Evidence grade C
- ATP (Peak ATP)Oral 'ATP' that doesn't reach muscle as ATP — small, mostly industry-linked performance signals.Evidence grade D
Sources
This entry lists no references of its own — it is assembled from the entries it links to, whose sources are on their pages.
Last revised . A grade is this entry's reading of the evidence, not medical advice.