Evidence brief · Supplement
Coenzyme Q10 for Migraine prophylaxis
Evidence grade C — Modest
- Overall grade
- Grade C
- Last revised
- 1
- graded outcome
- 0
- references listed
Assembled by the app from other entries in this library. It adds no evidence of its own — follow the links to the entries it draws on.
1 at grade C — 1 graded row
What is known
Each outcome with its grade (how strong the evidence is, A to D), the size of the effect where the entry records one, and how often studies agree.
- Migraine prophylaxisEvidence grade C
Modest
Smallmixed
What is uncertain
Read off the same rows as above. Nothing here is added that the entry does not itself record.
- Thin evidence: Migraine prophylaxis (grade C).
The evidence in words
The verdict
For migraine prophylaxis, Coenzyme Q10 earns evidence grade C (small effect, mixed consistency) — the evidence is limited or mixed. Modest
How it might work
It shuttles electrons in ATP production and protects membranes from oxidative damage; statins lower CoQ10 because they block a shared synthesis pathway.
How to use it
100–200 mg/day (ubiquinol may absorb better) with a fatty meal.
Safety & cautions
Very safe; mild GI upset. May slightly reduce warfarin's effect (monitor INR).
Bottom line
Best value in heart failure (under care) and as a low-risk trial for statin muscle aches. Take with fat; ubiquinol if absorption is a concern.
How it is used
As the entry records it, from the studies it summarises. Not a recommendation for you — doses that suit a trial population may not suit you.
- Standard
- 100–200 mg/day with fat.
Goes with
- Coenzyme Q10Read the full Coenzyme Q10 monographEvidence grade B
Related reading
Entries that share this one's tags or conditions.
- Coenzyme Q10 for Chronic heart failureEvidence grade B — Adjunct, under careEvidence grade B
- Coenzyme Q10 for Heart failure eventsEvidence grade B — Q-SYMBIO positiveEvidence grade B
- Coenzyme Q10 for Statin muscle symptomsEvidence grade C — Worth a trialEvidence grade C
- Coenzyme Q10: dosage and how to take it100–200 mg/day with fat.Evidence grade B
Sources
This entry lists no references of its own — it is assembled from the entries it links to, whose sources are on their pages.
Last revised . A grade is this entry's reading of the evidence, not medical advice.