Evidence brief · Supplement
Capsaicin / Capsimax for Neuropathic / OA pain (topical)
Evidence grade B — Established
- Overall grade
- Grade B
- Last revised
- 1
- graded outcome
- 0
- references listed
Assembled by the app from other entries in this library. It adds no evidence of its own — follow the links to the entries it draws on.
1 at grade B — 1 graded row
What is known
Each outcome with its grade (how strong the evidence is, A to D), the size of the effect where the entry records one, and how often studies agree.
- Neuropathic / OA pain (topical)Evidence grade B
Established
Moderatehigh
The evidence in words
The verdict
For neuropathic / oa pain (topical), Capsaicin / Capsimax earns evidence grade B (moderate effect, high consistency) — there is real evidence here. Established
How it might work
It activates TRPV1 receptors, modestly raising energy expenditure and fat oxidation and reducing appetite; topically it desensitizes pain fibers.
How to use it
Safety & cautions
GI burning at high oral doses; topical can sting. Beadlet forms reduce oral discomfort.
Bottom line
A minor metabolic nudge and appetite blunter orally; a genuinely useful topical for certain pain. Don't expect real weight loss from capsules.
Goes with
- Capsaicin / CapsimaxRead the full Capsaicin / Capsimax monographEvidence grade C
Related reading
Entries that share this one's tags or conditions.
- Capsaicin / Capsimax for Energy expenditure / fat oxidationEvidence grade C — MinorEvidence grade C
- Capsaicin / Capsimax: side effects, safety & interactionsGI burning at high oral doses; topical can sting. Beadlet forms reduce oral discomfort.Evidence grade C
- CLA (Conjugated Linoleic Acid) for Fat lossEvidence grade D — Not meaningfulEvidence grade D
- Forskolin for Fat lossEvidence grade D — Weak, unreplicatedEvidence grade D
Sources
This entry lists no references of its own — it is assembled from the entries it links to, whose sources are on their pages.
Last revised . A grade is this entry's reading of the evidence, not medical advice.