Compound or practice · Supplement
Dong Quai
A classic 'female tonic' whose menopause evidence is weak — and it interacts with blood thinners.
- Overall grade
- Grade D
- Last revised
- 1
- graded outcome
- 0
- references listed
A structured monograph in Prometheus's bundled library. Its grades are the monograph's own reading of the evidence, not a peer-reviewed review.
1 at grade D — 1 graded row
What is known
Each outcome with its grade (how strong the evidence is, A to D), the size of the effect where the entry records one, and how often studies agree.
- Menopausal symptomsEvidence grade D
Largely negative
Triviallow
What is uncertain
Read off the same rows as above. Nothing here is added that the entry does not itself record.
- Thin evidence: Menopausal symptoms (grade D).
- Caution with Anticoagulants (warfarin): Coumarins add bleeding risk.
Interactions
Documented pairings with supplements and medicines. A medicine on this list is a conversation for whoever prescribes it.
Anticoagulants (warfarin)Caution
Coumarins add bleeding risk.
The evidence in words
What it is
Dong quai (Angelica sinensis) is a Chinese herb used for menstrual and menopausal symptoms.
How it works
Contains coumarins and phytochemicals with proposed (but unclear) hormonal and vascular effects.
What the evidence shows
Controlled trials, including for menopausal hot flashes, have been largely negative for dong quai alone. Its coumarin content raises bleeding risk with anticoagulants.
Safety & interactions
Bleeding risk with warfarin/antiplatelets; photosensitivity. warfarin — Coumarins add bleeding risk.
Bottom line
A traditional women's tonic that underperforms in trials and interacts with blood thinners. Better menopause options exist.
Related reading
Entries that share this one's tags or conditions.
- Black CohoshA menopausal hot-flash botanical with genuinely divided trials and rare liver-safety signals.Evidence grade C
- Dong Quai for Menopausal symptomsEvidence grade D — Largely negativeEvidence grade D
- Dong Quai: side effects, safety & interactionsBleeding risk with warfarin/antiplatelets; photosensitivity.Evidence grade D
- Black Cohosh for Menopausal hot flashesEvidence grade C — Divided trialsEvidence grade C
Sources
This entry lists no references of its own.
Last revised . A grade is this entry's reading of the evidence, not medical advice.