Venous insufficiency: what the evidence supports and Pycnogenol (Pine Bark)

Each entry’s own grades, side by side. A grade says how strong the evidence is for one outcome — it does not rank one entry over the other.

Outcome map

Venous insufficiency: what the evidence supports

2 graded interventions for venous insufficiency, ranked by strength of evidence.

Grade C2 graded outcomesrevised Jul 10, 2026

Assembled by the app from other entries in this library. It adds no evidence of its own — follow the links to the entries it draws on.

Compound or practice

Pycnogenol (Pine Bark)

A pine-bark polyphenol with broad small-trial signals for circulation, blood pressure, and skin — much of it single-source.

Grade C3 graded outcomesrevised Jul 10, 2026

A structured monograph in Prometheus's bundled library. Its grades are the monograph's own reading of the evidence, not a peer-reviewed review.

Swap the two

Graded in both

Outcomes are matched by name. Two entries can describe the same outcome in different words, so one listed further down may still be graded in the other.

No outcome has the same name in both entries. They may still overlap under different wording — read the two lists below.

Graded only in Venous insufficiency: what the evidence supports

  • Gotu Kola Small effectEvidence grade C
  • Pycnogenol (Pine Bark) Small effectEvidence grade C

Graded only in Pycnogenol (Pine Bark)

  • Venous insufficiency Small effectEvidence grade C
  • Blood pressure Small effectEvidence grade C
  • Skin elasticity/UV Small effectEvidence grade C

What each entry says about the other

  • Venous insufficiency: what the evidence supports’s entry · Goes with: Grade C

Both columns are read from the entries as they stand in this library. A comparison is not advice to take either one, and it is no substitute for a clinician who knows the person.