PrometheusGeneral

Caffeine: side effects, safety & interactions and Rhodiola Rosea

Each entry’s own grades, side by side. A grade says how strong the evidence is for one outcome — it does not rank one entry over the other.

Safety

Caffeine: side effects, safety & interactions

Safe for most in moderation; excess causes anxiety, palpitations, and insomnia. Dependence and withdrawal (headache, fat

Grade A0 graded outcomesrevised Jul 10, 2026

Assembled by the app from other entries in this library. It adds no evidence of its own — follow the links to the entries it draws on.

Compound or practice

Rhodiola Rosea

A stimulating adaptogen with the best fatigue evidence among the herbal 'stress' supplements — daytime energy without ashwagandha's flatness.

Grade B3 graded outcomesrevised Jul 10, 2026

A structured monograph in Prometheus's bundled library. Its grades are the monograph's own reading of the evidence, not a peer-reviewed review.

Swap the two

Graded in both

Outcomes are matched by name. Two entries can describe the same outcome in different words, so one listed further down may still be graded in the other.

No outcome has the same name in both entries. They may still overlap under different wording — read the two lists below.

Graded only in Caffeine: side effects, safety & interactions

None — every outcome it grades is graded in both.

Graded only in Rhodiola Rosea

  • Fatigue / burnout Moderate effectEvidence grade B
  • Stress symptoms Small effectEvidence grade B
  • Cognition under fatigue Small effectEvidence grade C

Conditions

Only in Caffeine: side effects, safety & interactions

None.

Only in Rhodiola Rosea

What each entry says about the other

  • Caffeine: side effects, safety & interactions’s entry · Watch with: Both activating — stack low-dose.

Both columns are read from the entries as they stand in this library. A comparison is not advice to take either one, and it is no substitute for a clinician who knows the person.