Riboflavin (B2) and Butterbur
Each entry’s own grades, side by side. A grade says how strong the evidence is for one outcome — it does not rank one entry over the other.
Compound or practice
Riboflavin (B2)
A B-vitamin with one standout use: high-dose riboflavin genuinely prevents migraines.
Grade B2 graded outcomesrevised Jul 10, 2026
A structured monograph in Prometheus's bundled library. Its grades are the monograph's own reading of the evidence, not a peer-reviewed review.
Compound or practice
Butterbur
Solid evidence for migraine prevention and allergic rhinitis — but only PA-free products are safe.
Grade B2 graded outcomesrevised Jul 10, 2026
A structured monograph in Prometheus's bundled library. Its grades are the monograph's own reading of the evidence, not a peer-reviewed review.
Graded in both
Outcomes are matched by name. Two entries can describe the same outcome in different words, so one listed further down may still be graded in the other.
No outcome has the same name in both entries. They may still overlap under different wording — read the two lists below.
Graded only in Riboflavin (B2)
- Migraine frequency Moderate effectEvidence grade B
- Deficiency Large effectEvidence grade A
Graded only in Butterbur
- Migraine prevention Moderate effectEvidence grade B
- Allergic rhinitis Moderate effectEvidence grade B
Conditions
- MigraineRiboflavin (B2): ImprovesEvidence grade BButterbur: ImprovesEvidence grade B
Only in Riboflavin (B2)
None.
Only in Butterbur
None.
What each entry says about the other
Neither entry records anything about the other. That is not evidence that they do not interact — only that neither entry says.
Both columns are read from the entries as they stand in this library. A comparison is not advice to take either one, and it is no substitute for a clinician who knows the person.