Magnesium and Vitamin B6
Each entry’s own grades, side by side. A grade says how strong the evidence is for one outcome — it does not rank one entry over the other.
Compound or practice
Magnesium
A cofactor in 300+ reactions that a large fraction of adults under-consume — real, modest benefits for sleep, blood pressure, and migraine.
Grade B4 graded outcomesrevised Jul 10, 2026
A structured monograph in Prometheus's bundled library. Its grades are the monograph's own reading of the evidence, not a peer-reviewed review.
Compound or practice
Vitamin B6
A cofactor for neurotransmitter and amino-acid metabolism; genuinely useful for pregnancy nausea and PMS, toxic if chronically megadosed.
Grade B3 graded outcomesrevised Jul 10, 2026
A structured monograph in Prometheus's bundled library. Its grades are the monograph's own reading of the evidence, not a peer-reviewed review.
Graded in both
Outcomes are matched by name. Two entries can describe the same outcome in different words, so one listed further down may still be graded in the other.
No outcome has the same name in both entries. They may still overlap under different wording — read the two lists below.
Graded only in Magnesium
- Correcting low status Moderate effectEvidence grade A
- Blood pressure Small effectEvidence grade B
- Migraine prophylaxis Moderate effectEvidence grade B
- Subjective sleep Small effectEvidence grade B
Graded only in Vitamin B6
- Pregnancy nausea Moderate effectEvidence grade B
- PMS symptoms Small effectEvidence grade B
- Homocysteine Small effectEvidence grade B
Conditions
Only in Magnesium
- Migraine May improveEvidence grade B
- Hypertension May improveEvidence grade B
- Insomnia May improveEvidence grade C
Only in Vitamin B6
None.
What each entry says about the other
- Vitamin B6’s entry · Works together: Common PMS pairing; complementary mechanisms.
- Vitamin B6’s entry · Goes with: Common PMS pairing; complementary mechanisms.
Both columns are read from the entries as they stand in this library. A comparison is not advice to take either one, and it is no substitute for a clinician who knows the person.