PrometheusGeneral

Ashwagandha + Benzodiazepines: use with caution and Ashwagandha

Each entry’s own grades, side by side. A grade says how strong the evidence is for one outcome — it does not rank one entry over the other.

Interaction

Ashwagandha + Benzodiazepines: use with caution

Additive sedation on top of the sedative's effect.

Grade B0 graded outcomesrevised Jul 10, 2026

Assembled by the app from other entries in this library. It adds no evidence of its own — follow the links to the entries it draws on.

Compound or practice

Ashwagandha

The best-evidenced adaptogen for cortisol and stress — with a real question mark on long-term use.

Grade B5 graded outcomesrevised Jun 15, 2026

A hand-written entry in Prometheus's bundled library. Its grades are the entry's own reading of the evidence, not a peer-reviewed review.

Swap the two

Graded in both

Outcomes are matched by name. Two entries can describe the same outcome in different words, so one listed further down may still be graded in the other.

No outcome has the same name in both entries. They may still overlap under different wording — read the two lists below.

Graded only in Ashwagandha + Benzodiazepines: use with caution

None — every outcome it grades is graded in both.

Graded only in Ashwagandha

  • Perceived stress / anxiety Moderate effectEvidence grade A
  • Cortisol reduction Moderate effectEvidence grade B
  • Sleep quality Small effectEvidence grade B
  • Testosterone (stressed men) Small effectEvidence grade C
  • Long-term safety (>6 months) Unclear effectEvidence grade D

Conditions

Only in Ashwagandha + Benzodiazepines: use with caution

None.

Only in Ashwagandha

What each entry says about the other

  • Ashwagandha + Benzodiazepines: use with caution’s entry · Watch with: About Ashwagandha

Both columns are read from the entries as they stand in this library. A comparison is not advice to take either one, and it is no substitute for a clinician who knows the person.