Caffeine for Alertness / reaction time and Caffeine

Each entry’s own grades, side by side. A grade says how strong the evidence is for one outcome — it does not rank one entry over the other.

Evidence brief

Caffeine for Alertness / reaction time

Evidence grade A — Acute, tolerance-limited

Grade A1 graded outcomerevised Jul 10, 2026

Assembled by the app from other entries in this library. It adds no evidence of its own — follow the links to the entries it draws on.

Compound or practice

Caffeine

The most-used and best-evidenced cognitive and physical stimulant on earth — precise dosing and a hard afternoon cutoff are the whole skill.

Grade A4 graded outcomesrevised Jul 10, 2026

A structured monograph in Prometheus's bundled library. Its grades are the monograph's own reading of the evidence, not a peer-reviewed review.

Swap the two

Graded in both

Outcomes are matched by name. Two entries can describe the same outcome in different words, so one listed further down may still be graded in the other.

OutcomeCaffeine for Alertness / reaction timeCaffeine
Alertness / reaction time
Evidence grade AModerate effecthighAcute, tolerance-limited
Evidence grade AModerate effecthighAcute, tolerance-limited

Graded only in Caffeine for Alertness / reaction time

None — every outcome it grades is graded in both.

Graded only in Caffeine

  • Endurance performance Moderate effectEvidence grade A
  • Strength / power Small effectEvidence grade B
  • Sleep (afternoon dosing) Moderate effectEvidence grade A

What each entry says about the other

  • Caffeine for Alertness / reaction time’s entry · Goes with: Read the full Caffeine monograph

Both columns are read from the entries as they stand in this library. A comparison is not advice to take either one, and it is no substitute for a clinician who knows the person.