Coenzyme Q10 and Red Yeast Rice
Each entry’s own grades, side by side. A grade says how strong the evidence is for one outcome — it does not rank one entry over the other.
Compound or practice
Coenzyme Q10
A mitochondrial cofactor with its best evidence in heart failure and statin-associated muscle symptoms.
Grade B3 graded outcomesrevised Jul 10, 2026
A structured monograph in Prometheus's bundled library. Its grades are the monograph's own reading of the evidence, not a peer-reviewed review.
Compound or practice
Red Yeast Rice
A supplement that lowers LDL because it literally contains a statin — same benefits, same risks, minus the dose control.
Grade B2 graded outcomesrevised Jul 10, 2026
A structured monograph in Prometheus's bundled library. Its grades are the monograph's own reading of the evidence, not a peer-reviewed review.
Graded in both
Outcomes are matched by name. Two entries can describe the same outcome in different words, so one listed further down may still be graded in the other.
No outcome has the same name in both entries. They may still overlap under different wording — read the two lists below.
Graded only in Coenzyme Q10
- Heart failure events Moderate effectEvidence grade B
- Statin muscle symptoms Small effectEvidence grade C
- Migraine prophylaxis Small effectEvidence grade C
Graded only in Red Yeast Rice
- LDL cholesterol Moderate effectEvidence grade A
- Cardiovascular events Moderate effectEvidence grade B
Conditions
Only in Coenzyme Q10
- Chronic heart failure May improveEvidence grade B
Only in Red Yeast Rice
None.
What each entry says about the other
- Red Yeast Rice’s entry · Depletes a nutrient: Like all statins, lowers CoQ10.
- Red Yeast Rice’s entry · Watch with: Like all statins, lowers CoQ10.
Both columns are read from the entries as they stand in this library. A comparison is not advice to take either one, and it is no substitute for a clinician who knows the person.