PrometheusGeneral

Caffeine + L-Theanine and Sleep architecture

Each entry’s own grades, side by side. A grade says how strong the evidence is for one outcome — it does not rank one entry over the other.

Compound or practice

Caffeine + L-Theanine

The best-documented nootropic stack there is: coffee's focus without the jitter tax.

Grade B4 graded outcomesrevised Jun 12, 2026

A hand-written entry in Prometheus's bundled library. Its grades are the entry's own reading of the evidence, not a peer-reviewed review.

Compound or practice

Sleep architecture

The recovery system everything else compounds on — deep and REM timing matter more than raw hours.

Grade A4 graded outcomesrevised Jun 28, 2026

A hand-written entry in Prometheus's bundled library. Its grades are the entry's own reading of the evidence, not a peer-reviewed review.

Swap the two

Graded in both

Outcomes are matched by name. Two entries can describe the same outcome in different words, so one listed further down may still be graded in the other.

No outcome has the same name in both entries. They may still overlap under different wording — read the two lists below.

Graded only in Caffeine + L-Theanine

  • Sustained attention Moderate effectEvidence grade B
  • Reaction time Small effectEvidence grade A
  • Jitter / anxiety reduction vs caffeine alone Moderate effectEvidence grade B
  • Sleep harm from late dosing Large effectEvidence grade A

Graded only in Sleep architecture

  • Insomnia severity (CBT-I components) Large effectEvidence grade A
  • Deep-sleep minutes (schedule consistency) Moderate effectEvidence grade A
  • Next-day cognition Moderate effectEvidence grade A
  • REM cost of evening alcohol Moderate effectEvidence grade A

Conditions

  • HypertensionCaffeine + L-Theanine: May worsenEvidence grade CSleep architecture: ImprovesEvidence grade B

Only in Caffeine + L-Theanine

Only in Sleep architecture

What each entry says about the other

  • Caffeine + L-Theanine’s entry · Watch with: Late dosing is the single most common self-inflicted sleep wound
  • Sleep architecture’s entry · Watch with: Respect the 8–10h cutoff or the stack pays for itself in deep sleep

Both columns are read from the entries as they stand in this library. A comparison is not advice to take either one, and it is no substitute for a clinician who knows the person.