Alpha-Lipoic Acid and Alpha-Lipoic Acid + Metformin: use with caution
Each entry’s own grades, side by side. A grade says how strong the evidence is for one outcome — it does not rank one entry over the other.
Compound or practice
Alpha-Lipoic Acid
An antioxidant with genuine evidence for diabetic neuropathy symptoms and modest insulin-sensitivity effects.
Grade B2 graded outcomesrevised Jul 10, 2026
A structured monograph in Prometheus's bundled library. Its grades are the monograph's own reading of the evidence, not a peer-reviewed review.
Interaction
Alpha-Lipoic Acid + Metformin: use with caution
Additive glucose lowering — watch for lows.
Grade B0 graded outcomesrevised Jul 10, 2026
Assembled by the app from other entries in this library. It adds no evidence of its own — follow the links to the entries it draws on.
Graded in both
Outcomes are matched by name. Two entries can describe the same outcome in different words, so one listed further down may still be graded in the other.
No outcome has the same name in both entries. They may still overlap under different wording — read the two lists below.
Graded only in Alpha-Lipoic Acid
- Diabetic neuropathy symptoms Moderate effectEvidence grade B
- Insulin sensitivity / glucose Small effectEvidence grade B
Graded only in Alpha-Lipoic Acid + Metformin: use with caution
None — every outcome it grades is graded in both.
Conditions
Only in Alpha-Lipoic Acid
- Diabetic neuropathy ImprovesEvidence grade B
Only in Alpha-Lipoic Acid + Metformin: use with caution
None.
What each entry says about the other
- Alpha-Lipoic Acid + Metformin: use with caution’s entry · Watch with: About Alpha-Lipoic Acid
Both columns are read from the entries as they stand in this library. A comparison is not advice to take either one, and it is no substitute for a clinician who knows the person.