Compound or practice · Supplement

Bergamot (Citrus Bergamia)

A citrus polyphenol extract with promising LDL and triglyceride data — an emerging natural lipid helper.

Overall grade
Grade C
Last revised
2
graded outcomes
0
references listed

A structured monograph in Prometheus's bundled library. Its grades are the monograph's own reading of the evidence, not a peer-reviewed review.

3 at grade C — 3 graded rows

What is known

Each outcome with its grade (how strong the evidence is, A to D), the size of the effect where the entry records one, and how often studies agree.

  • LDL / triglyceridesEvidence grade C

    Promising

    Moderatemixed

  • HDLEvidence grade C

    Modest rise

    Smallmixed

Conditions

How the entry reads its effect on diagnosed conditions: the direction first, then the grade. Never a substitute for the person who treats you.

  • Dyslipidemia May improveAdjunctGrade C

What is uncertain

Read off the same rows as above. Nothing here is added that the entry does not itself record.

  • Thin evidence: LDL / triglycerides (grade C); HDL (grade C).
  • Caution with Statins: Overlapping lipid mechanisms — coordinate.

Interactions

Documented pairings with supplements and medicines. A medicine on this list is a conversation for whoever prescribes it.

  • StatinsCaution

    Overlapping lipid mechanisms — coordinate.

The evidence in words

What it is

Bergamot polyphenol extract is derived from the bergamot orange and used for cholesterol.

How it works

Its flavonoids inhibit cholesterol synthesis and improve lipid handling, with statin-like partial mechanisms.

What the evidence shows

Several trials show reductions in LDL and triglycerides and improved HDL, sometimes meaningfully; studies are small and often regional. Among the more promising natural lipid agents.

How to use it

500–1,000 mg standardized polyphenols daily.

Safety & interactions

Generally safe; theoretical additive effect with statins. statins — Overlapping lipid mechanisms — coordinate.

Bottom line

A promising natural option for lipids with real, if small-trial, data. Reasonable adjunct.

How it is used

As the entry records it, from the studies it summarises. Not a recommendation for you — doses that suit a trial population may not suit you.

Standard
500–1,000 mg standardized daily.

Entries that share this one's tags or conditions.

  • Red Yeast RiceA supplement that lowers LDL because it literally contains a statin — same benefits, same risks, minus the dose control.Evidence grade B
  • Artichoke Leaf ExtractA digestive-and-cholesterol botanical with modest LDL and dyspepsia data.Evidence grade C
  • BerberineA plant alkaloid that behaves like a metabolic drug — real glucose and lipid effects, and it deserves drug-level caution.Evidence grade B
  • Bergamot (Citrus Bergamia) for DyslipidemiaEvidence grade C — AdjunctEvidence grade C

Sources

This entry lists no references of its own.

Last revised . A grade is this entry's reading of the evidence, not medical advice.